Researchers from TMDU find that CD22 restores B cell function in B cell receptor (BCR) signaling deficiencies by interacting with cis-ligands and upregulating BCR expression, thereby paradoxically ...
Older patients and risk of developing and dying from bleomycin-induced lung toxicity. This is an ASCO Meeting Abstract from the 2014 ASCO Annual Meeting I. This abstract does not include a full text ...
A new method to assess the status of immune responses to specific antigens in detail by analysis using the B cell receptor (BCR) repertoire(*1) has been developed by a research group, consisting of ...
Cellecta, Inc. today announced the launch of the DriverMap™ Adaptive Immune Receptor (AIR) TCR and BCR kits, a family of multiplex-PCR, NGS-based assays that enable profiling of up to all seven T-cell ...
B Cells are a type of lymphocyte whose primary purpose is to generate highly specific antibodies in response to a foreign antigen. B Cells are a type of lymphocyte whose primary purpose is to generate ...
In a recent study published in Vaccines, researchers evaluated immune responses by B lymphocytes to Pfizer’s severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) mRNA (messenger ribonucleic ...
The prominent role of the BCR signaling in promoting B-CLL cell survival has prompted new therapeutic strategies targeted to signalosome elements. In particular, the most advanced BCR-signaling ...
The KLHL14 gene acquires frequent inactivating mutations in mature B cell malignancies, especially in the MYD88L265P, CD79B mutant (MCD) genetic subtype of diffuse large B cell lymphoma (DLBCL), which ...
B lymphocytes have the ability to sense thousands of structurally different antigens and produce cognate antibodies against these molecules. For this they carry on their surface multiple copies of the ...
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