Resting brain stem cells hardly differ from normal astrocytes, which support the nerve cells in the brain. How can almost identical cells perform such different functions? The key lies in the ...

Resting brain stem cells hardly differ from normal astrocytes, which support the nerve cells in the brain. How can almost identical cells perform such different functions? The key lies in the ...

Back in 1942, the term epigenetics was introduced by Conrad Waddington to present a picture of cell development, one in which cells descended a hillside and followed diverging valley paths before ...

Paper in Cloning and Stem Cells shows that animal eggs do not support specific reprogramming toward the normal human embryonic state. Investigators at Advanced Cell Technology (ACTC) have found that ...

Genome remethylation is essential for mammalian development but specific reasons are unclear. Here we examined embryonic stem (ES) cell fate in the absence of de novo DNA methyltransferases. We ...

Global DNA-methylation is affected in G- cells. Global methylation level analysis in G− and G+ condition. (A) Bart chart representing the methylation level of individual sample (y-axis, 1 = 100%) in ...