Here, we define a gene regulatory network for Hoxa2, responsible for temporal and spatial expression in hindbrain development. Hoxa2 plays an important role in regulating the regional identity of ...

“Expression tells us what cells do, but regulatory DNA tells us where they come from, how they develop, and which germ layer ...

Elucidating the relationship between the sequences of non-coding regulatory elements and their target genes is key to understanding gene regulation and its variation between plant species and ecotypes ...

Some sequences in the genome cause genes to be switched on or off. Until now, each of these gene switches, or so-called enhancers, was thought to have its own place on the DNA. Different enhancers are ...

Triglia discusses her research at the intersection of genetics, epigenetics, single-cell genomics and computational biology.

On its 125th anniversary, Science magazine posed 125 unsolved scientific questions, among which “What genetic changes made us uniquely human?” was listed as one of the 25 core problems. Yet the ...

Gene regulation is the process by which cells control the expression of their genes, determining when, where, and to what extent each gene is expressed. It is a fundamental mechanism that allows cells ...

Cancer has long been treated as a mass of rogue cells, but the real power lies in the intricate communication networks ...

The firm submitted non-clinical and clinical modules of its rolling BLA for DTX401 in August and has now submitted the chemistry, manufacturing, and controls module.

Plant trichomes, the hair-like structures covering aerial organs, serve as protective barriers against environmental stresses.