Although genome-wide association studies (GWASs) have identified numerous loci associated with complex traits, imprecise modeling of the genetic relatedness within study samples may cause substantial ...
Mixed linear model (MLM) methods have proven useful in controlling for population structure and relatedness within genome-wide association studies. However, MLM-based methods can be computationally ...
The generalized linear model (Nelder & Wedderburn, 1972) has become an elegant and practical option to classical least-squares linear model building. We consider the specific problem of generalized ...