FAS, fatty acid synthase; FATP, fatty acid transporter protein; GPCR, G protein-coupled receptor; LPC, lysophosphatidylcholine; LXR, liver X receptor; PPARγ, peroxisome proliferator-activated receptor ...
Breast cancer remains the most prevalent malignancy among women worldwide, posing a critical challenge to global health. Amid the complexities of this disease, an emerging focus on metabolic ...
Phase 1a/1b study in 97 patients demonstrates mitochondrial metabolic reprogramming induced by BPM31510-IV and supports advancement in multiple ...
Leuven, 11 March 2025 – Solid tumors often provide a challenging environment for the T cells of our immune system. By reprogramming the metabolism of T cells, scientists at the VIB-KU Leuven Center ...
The field of cancer research is increasingly exploring the intricate intersections among epigenetics, cancer metabolism, and immunotherapy. These ...
The Warburg effect describes how cancer cells switch from oxidative phosphorylation to glycolysis even in oxygen-rich conditions, producing massive ...
A Ludwig Cancer Research study has identified a complex chain of molecular chatter by which cancer cells, exploiting ordinary metabolic processes, program one set of noncancerous cells to manipulate ...
Metabolic reprogramming in the tumor microenvironment shapes immune function and therapy resistance, offering insights into ...
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