A new CRISPR approach can control genes without cutting DNA, opening a safer path for treating genetic diseases. A newly ...

People are often encouraged to “know their status,” however this healthy habit can be applied to more than just safe-sex practices. Although they are not the only community who suffers with sickle ...

Genetic variability and sex-specific differences may play a role in sickle cell disease (SCD)-related pain; however, more research is needed. In the present study, saliva samples from 59 adults with ...

Exa-cel, a new CRISPR-based treatment, modifies the genes of the patient's stem cells to induce them to produce fetal hemoglobin. I have a long-standing interest in sickle cell anemia, a genetic ...

At the Cleveland Clinic, doctors are using a one-time gene-editing therapy that alters a patient’s own blood-forming stem cells to correct the genetic mutation responsible for the disease. Physicians ...

Despite a Trump administration push, there are few facilities offering the complex treatment in the rural areas where many ...

Beam Therapeutics advances base-editing pipeline with risto-cel studies and FDA designations, but no approved products and rising competition loom.

Britain's medicines regulator has authorized the world's first gene therapy treatment for sickle cell disease, in a move that could offer relief to thousands of people with the crippling disease in ...

Gene editing has moved from theory to bedside with a speed that would have seemed impossible a decade ago. A new wave of ...

National Institutes of Health (NIH) researchers and collaborators have found that being a carrier for sickle cell disease, known as having sickle cell trait, increases the risk of blood clots, a risk ...

A parasite that causes malaria is halted by sickle cells and makes people who carry the sickle cell trait more resistant to the disease. This is why sickle cell trait also occurs more in people who ...