Artificial intelligence has just redrawn the map of our genome’s control room, revealing hundreds of thousands of tiny DNA ...

DNA- and RNA-binding proteins (DRBPs) constitute a significant fraction of cellular proteins and have important roles in cells. Their functions include control of transcription and translation, DNA ...

The structure of the B-form DNA double helix has been known for over 60 years 1, yet DNA metabolism requires deviations, sometimes extreme, from this canonical form 2,3,4. Studies of DNA are typically ...

One of the most detailed 3D maps of how the human chromosomes are organized and folded within a cell's nucleus is published ...

The researchers focused on the structure and dynamics of kinetoplast DNA, the mitochondrial genome of Trypanosomes, with an experimental study led by Edinburgh and a computational analysis that ...

Inside cells, DNA twists and coils itself into a variety of different secondary structures—including i-motifs (iMs) and G-quadruplexes (G4s)—that influence gene expression. Some drugs target these ...