Viruses are small obligate intracellular parasites with either a RNA or DNA genome that are surrounded by a protective protein coat and transfer their genetic material to infected cells. Lentivirus ...
Thorough lentivirus characterization is essential for generating the highest quality gene therapy. Traditional methods only look at one piece of the puzzle, require purified samples, and can take days ...
Lentivirus is a genus in the family of Retroviridae that is very suitable for remodeling into gene transfer vectors due to its stable transgene expression, the ability to reach the nuclei of the ...
Metachromatic leukodystrophy (MLD) is a rare genetic disorder caused by the deficiency of arylsulfatase A (ARSA) or its activator prosaposin (PSAP). This leads to the accumulation of sulfatides in the ...
Cystic fibrosis (CF) is caused by recessive mutations in the CFTR (cystic fibrosis transmembrane conductance regulator) gene, which encodes a chloride channel residing in the epithelium of multiple ...
Lentiviruses have the unique ability amongst retroviruses of being able to infect non-cycling cells. Vectors derived from lentiviruses have provided a huge advancement in technology and seemingly ...
Lentiviral transduction is a popular delivery platform for applications such as CAR-T cell engineering or CRISPR-Cas9 gene editing, as it can transduce both dividing and non-dividing cells and ...
During the virtual Bioprocessing Summit in August, Cytiva reported that its new filtration process has advantages compared to traditional centrifuge approaches for removing viruses from suspension ...
Lentiviruses cause a variety of chronic diseases in mammals ranging from HIV/AIDS in humans to various neurological disorders in primates, yet little is known of their evolutionary history and origin.
Through a recent agreement with Oxford Genetics, Aldevron will now be providing the plasmids necessary for lentivirus production to their customers, according to an announcement made last week at the ...
GERMANTOWN, MD AND CHICAGO, IL / ACCESS Newswire / December 16, 2025 / uBriGene Biosciences, a leading global lentivirus CDMO ...
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