One of the most detailed 3D maps of how the human chromosomes are organized and folded within a cell's nucleus is published ...

If stretched out, human DNA would be about 2 meters long. For this long strand to fit inside the cell nucleus, which is about ...

Although it also performs some functions in men, estrogen, the main female sex hormone, is involved in a myriad of processes, ...

Researchers at the CNIO show that oestrogens regulate gene expression by changing DNA supercoiling. Hormone-activated ...

What makes someone a "morning lark" or a "night owl?" Why does jet lag hit us so hard, and why do some people struggle each ...

A team of researchers has generated one of the most detailed 3D maps of human chromosomes, cataloging over 140,000 DNA looping interactions.

The research represents a major step forward in revealing how the three dimensional form of DNA shapes the way human biology functions. In a major step toward understanding how the physical form of ...

There is a huge amount of DNA in most human cells, and that DNA has to be carefully compacted and organized so that it will ...

Diabetic kidney disease affects a growing proportion of people with diabetes and remains the leading cause of end-stage renal ...

Research reveals that five DNA letters can switch chromatin between fluid and solid-like states, influencing gene ...

Estrogens, the main female sex hormone, although they also perform some functions in men, are involved in a myriad of ...

This important study provides a detailed analysis of the transcriptional landscape of the mouse hippocampus in the context of various physiological states. The main conclusions have solid support: ...