While widely adopted for comprehensive transcriptome profiling, the methods of poly-A selected or ribodepleted RNA-sequencing may have key limitations, including input mass requirements, inefficient ...

RNA sequencing (RNA-seq) is a powerful tool in diagnosing Mendelian disorders, but the optimized sequencing depth for this technology has not yet been determined. In a new study published in the ...

Biomarker testing is central to oncology research and clinical care, driving targeted therapy development and personalized treatment. Next-generation sequencing (NGS) based approaches can detect ...

Takara Bio USA has expanded its instrument-free Trekker™ Single-Cell Spatial Mapping Kits for compatibility with formalin-fixed paraffin-embedded (FFPE) samples, one of the most common and trusted ...

Nearly a year after expanding from single cell omics solutions into spatial biology, Takara Bio USA has launched a series of updates to its product portfolio designed to bring its new class of spatial ...

Exploring biology in its native environment is perhaps the ideal scenario for generating better hypotheses about the cellular interactions that influence—and drive—healthy and diseased states, ...

Traditional PCR systems require users to set a specified number of cycles according to the assay and the input amount. As a result, input material must be quantified, and samples of varying inputs ...

When carrying out conventional PCR workflows users have to specify how many amplification cycles they need according to input quantity and assay type. This rigid structure is particularly difficult ...

Solitary Fibrous Tumors express a neuronal gene signature. (a) Table of the eight formalin-Fixed Paraffin-Embedded (FFPE) samples used for RNA-seq listing the sample ID, Age at surgery, Sex, Diagnosis ...

microRNAs are emerging as powerful biomarkers for precision medicine, offering valuable insights into disease mechanisms, diagnosis, prognosis, and treatment response. However, successful discovery ...