Research reveals that five DNA letters can switch chromatin between fluid and solid-like states, influencing gene ...
New ultra-detailed imaging exposes the hidden structure and behavior of chromatin condensates — and hints at how their failures may drive disease.
High-resolution imaging has revealed the internal layout of chromatin condensates, showing how DNA fibers fold and interact within these droplet-like structures. The findings connect molecular ...
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Chromatin accessibility maps reveal how stem cells drive myelodysplastic syndrome progression
Over the past few decades, advances in hematology have illuminated how a delicate balance between stem cell self-renewal and ...
There is a huge amount of DNA in most human cells, and that DNA has to be carefully compacted and organized so that it will ...
The nuclei of most human cells contains the entire genome, which would have a length of about six feet if it was fully extended. So this DNA has to be carefully compacted in cells, while still ...
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Researchers identify chromatin accessibility changes driving stem cell transformation in MDS
Over the past few decades, advances in hematology have illuminated how a delicate balance between stem cell self-renewal and ...
It's a common storytelling trope: the stubborn foe who is eventually revealed to be a much-needed friend. Biology has its own ...
Modern Engineering Marvels on MSN
140,000 DNA loops mapped with AI to predict genome folding
A game-changining achievement in genome science has identified over 140,000 distinct DNA loops in our cells, providing chromosome fold resolution that is among the best ever created. In this ongoing ...
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